Chloramphenicol Treatment for Rabbit Syphilis

Experimental rabbit syphilis.

Experimental Syphilis in the Rabbit

In a series of more than 200 rabbits in which generalized lesions were observed following local inoculation with Treponema pallidum, there were a number of animals in which characteristic lesions were noted upon mucous membranes or along mucocutaneous borders. These lesions were distributed with about equal frequency between the nose or nasolacrimal system and the eyelids on the one hand, and t...

Effects of griseofulvin in experimental rabbit syphilis.

We have previously reported the effects of some antibiotics on experimental rabbit syphilis (Fujita, Asada, and Amawashi, 1962). The recent resurgence of infectious syphilis has led us to look for more effective anti-luetic agents. From this point of view we are studying the ultrastructure of spirochaetes (Hasegawa, Sasahira, and Matsuura, 1965; Hasegawa and Sasahira, 1965; Hasegawa, Komura, an...

[Penicillin treatment of syphilis].

JAMA. 1944;126(2):63-67, 67-73, 73-80. In the follow-up to a preliminary report on the use of penicillin for early syphilis, Mahoney and colleagues presented the promising posttreatment observations of the original patients studied for periods in excess of 300 days. They also reported information on the treatment of an additional 100 patients. The accompanying papers in the same issue of JAMA r...

The Treatment of Syphilis